N-ethyl-4-methylpyridin-2-amine → HCID 178476385, compound

HRID 1279578Notes

Reaction equation

HRID 1279578 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].N=C1CC(C)CCN1.[CH2:13]([NH:15][C:16]1[CH:21]=[C:20]([CH3:22])[CH:19]=[CH:18][N:17]=1)[CH3:14]>>[C:1]([OH:4])(=[O:3])[CH3:2].[CH3:14][CH2:13][N:15]=[C:16]1[CH2:21][CH:20]([CH3:22])[CH2:19][CH2:18][NH:17]1

Participants

3

Reactant 2

HCID 18428456N-ethyl-4-methylpyridin-2-amineHCID 1784758702-Imino-4-methylpiperidine acetate

Product 1

HCID 178476385HCID 178476385, compound

Procedure

The method of preparation of 2-imino-4-methylpiperidine acetate was used to convert 2-(ethylamino)-4-methylpyridine to the title compound except platinum oxide was used as the catalyst. The analysis of the product, obtained as an oil, was found to be consistent with the proposed structure. MH+=141; 1H NMR (D2O): 3.40-3.10 (m, 2H); 3.00 (q, J=6 Hz, 2H); 2.50-2.40 (m, 1H); 2.10-1.90 (m, 1H); 1.83 (s, 3H); 1.80-1.65 (m, 4H); 1.40-1.20 (m 1H); 1.02 (t, J=6 Hz, 3H); 0.83 (d, J=6 Hz, 3H).

Sources & evidence

ORD record
ord-36c403e4056f47a684474203a2675e3e
Source dataset
uspto-grants-2002_09
Patent number
US06448286B1

Reaction notes

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