4-Methyl-2-(propylamino)pyridine hydrochloride → HCID 178456746, compound

HRID 1279580Notes

Reaction equation

HRID 1279580 reaction equation
C(O)(=O)C.C(N=C1CC(C)CCN1)C.[ClH:15].[CH3:16][C:17]1[CH:22]=[CH:21][N:20]=[C:19]([NH:23][CH2:24][CH2:25][CH3:26])[CH:18]=1>>[ClH:15].[CH3:16][CH:17]1[CH2:22][CH2:21][NH:20][C:19](=[N:23][CH2:24][CH2:25][CH3:26])[CH2:18]1

Participants

3

Reactant 2

HCID 184284624-Methyl-2-(propylamino)pyridine hydrochlorideHCID 178476385HCID 178476385, compound

Product 1

HCID 178456746HCID 178456746, compound

Procedure

The method of preparation of 2-(ethylimino)-4-methylpiperidine acetate was used to convert 4-methyl-2-(propylamino)pyridine hydrochloride to the title compound. The product was obtained as a clear colorless oil which crystallized under EtOAc. The analysis of the product was found to be consistent with the proposed structure. MH+=155; 1H NMR (D2O): 3.45-3.20 (m, 2H); 3.05 (t, J=6 Hz, 2H); 2.60-2.45 (m, 1H); 2.20-2.00 (m,; 1.95-1.70 (m, 2H); 1.60-1.40 (m, 2H); 1.40-1.25 (m, 1H); 0.90 (d, J=6 Hz, 3H); 0.80 (t, J=6 Hz, 3H).

Sources & evidence

ORD record
ord-faf593aed4634820b92ac98c4c774679
Source dataset
uspto-grants-2002_09
Patent number
US06448286B1

Reaction notes

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