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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 12797Generated: October 30, 2026

Hydrochloric Acid → HCID 86615962, compound

https://huagongshe.com/reaction/12797

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 24759659HCID 24759659—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 86615962HCID 86615962—

Reaction Steps

5-(2-chloro-5-fluoro-3-pyridinyl)-1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-2,4(1H,3H)-pyrimidinedione was dissolved in dioxane and treated with 4N HCl in dioxane (2 eq), to give the title compound as a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07727988B2
Source datasetuspto-grants-2010_06
ORD IDord-bfec4a49d7ae4bbcb589024cb98da7ba
Source noteuspto-grants-2010_06