2-(4-chlorophenyl)ethenesulfonyl Chloride → Ethyl 2-{4-[2-(4-chlorostyrenesulphonylamino)-ethyl]-phenoxy}-2-methylpropionate

HRID 127976Notes

Reaction equation

HRID 127976 reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][C:5]([CH:6]=[CH:7][S:8](Cl)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[NH2:14][CH2:15][CH2:16][C:17]1[CH:31]=[CH:30][C:20]([O:21][C:22]([CH3:29])([CH3:28])[C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:19][CH:18]=1>>[Cl:1][C:2]1[CH:13]=[CH:12][C:5]([CH:6]=[CH:7][S:8]([NH:14][CH2:15][CH2:16][C:17]2[CH:18]=[CH:19][C:20]([O:21][C:22]([CH3:28])([CH3:29])[C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:30][CH:31]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 38443052-(4-chlorophenyl)ethenesulfonyl ChlorideHCID 19356632Ethyl 2-[4-(2-aminoethyl)-phenoxy]-2-methylpropionate

Product 1

HCID 54056868Ethyl 2-{4-[2-(4-chlorostyrenesulphonylamino)-ethyl]-phenoxy}-2-methylpropionate

Procedure

From p-chlorostyrenesulphonyl chloride and ethyl 2-[4-(2-aminoethyl)-phenoxy]-2-methylpropionate; colourless oil, nD20 =1.5625;

Sources & evidence

ORD record
ord-69f4a1eb8a4f4684913a4dea7432d1fc
Source dataset
uspto-grants-1981_03
Patent number
US04258058

Reaction notes

Loading…