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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 12798Generated: October 29, 2026

Hydrochloric Acid → HCID 86615963, compound

https://huagongshe.com/reaction/12798

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-(6-fluoro-2-pyridinyl)-1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-2,4(1H,3H)-pyrimidinedioneHCID 24759660—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 86615963HCID 86615963—

Reaction Steps

5-(6-fluoro-2-pyridinyl)-1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-2,4(1H,3H)-pyrimidinedione was dissolved in dioxane and treated with 4N HCl in dioxane (2 eq), to give the title compound as a off-white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07727988B2
Source datasetuspto-grants-2010_06
ORD IDord-0acf27fb60014e02954d893f36708184
Source noteuspto-grants-2010_06