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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1279831Generated: November 1, 2026

Trifluoroacetic acid → HCID 69779619, compound

https://huagongshe.com/reaction/1279831

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 59909779HCID 59909779—
SolventDichloromethaneHCID 6344—
ProductHCID 69779619HCID 69779619—

Reaction Steps

A solution of tert-butyl (3R)-6-cyclohexyl-3-{3-[7,8-dihydro[1,6]naphthyridin-6(5H)-ylcarbonyl]-1,2,4-oxadiazol-5-yl}hexanoate (Preparation 29) (281 mg, 0.58 mmol) in dichloromethane (4 ml) was treated with trifluoroacetic acid (1 ml) and the resulting mixture was stirred at room temperature under a nitrogen atmosphere for 17 hours. The solvent was removed under reduced pressure and the residue azeotroped from toluene to afford the title compound (245 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06448278B2
Source datasetuspto-grants-2002_09
ORD IDord-22457d8905834708932b8f160314ccd7
Source noteuspto-grants-2002_09