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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1279857Generated: November 4, 2026

Trifluoroacetic acid → HCID 69778090, compound

https://huagongshe.com/reaction/1279857

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 16749536HCID 16749536—
ProductHCID 69778090HCID 69778090—

Reaction Steps

tert-Butyl (3R)-6-cyclohexyl-3-[3-(2-pyridinylmethyl)-1,2,4-oxadiazol-5-yl]hexanoate (Preparation 58) (247 mg, 0.60 mmol) was treated with trifluoroacetic acid (7 ml) and the resulting mixture was stirred at room temperature under a nitrogen atmosphere for 4 hours. The solvent was removed under reduced pressure and the residue azeotroped from toluene then dichloromethane to afford the title compound as an oil (262 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06448278B2
Source datasetuspto-grants-2002_09
ORD IDord-78a90bbc934b45a6afe2e50727c6f73a
Source noteuspto-grants-2002_09