反应详情

A solution of dioctadecylamine (5.2 g., 0.01 mole), ethyl 4-bromobutyrate (1.95 g., 0.01 mole) and toluene (50 ml.) is heated at reflux for sixteen hours, then cooled and concentrated in vacuo to a semi-solid oil. The oil is triturated with ethylacetate, filtered, and the filtrate washed with water, then dried (Na2SO4). Removal of the solvent gives the product as an oil (3.7 g.).

1. temperatureat reflux for sixteen hours
2. temperaturecooled
3. concentrationconcentrated in vacuo to a semi-solid oil
4. customThe oil is triturated with ethylacetate
5. filtrationfiltered
6. washthe filtrate washed with water
7. dry with materialdried (Na2SO4)
8. customRemoval of the solvent