HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazide (H3N21-) → (S)-5-Nitrotryptophan amide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazide (H3N21-) | HCID 168365 | — |
| Reactant | (S)-5-Nitrotryptophan methyl ester hydrochloride | HCID 86585256 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (S)-5-Nitrotryptophan amide hydrochloride | HCID 86585255 | — |
Reaction Steps
(S)-5-Nitrotryptophan methyl ester hydrochloride (see example 47) was converted to the corresponding amide derivative following the procedure described in example 44 for the 5-hydroxy derivative. The amino amide was then converted to its hydrochloride salt using 4N HCl in dioxane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06448281B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-159e085e6e404d809be91006f364c820 |
| Source note | uspto-grants-2002_09 |