HCID 18429350, compound → HCID 18429180, compound

HRID 1280144Notes

Reaction equation

HRID 1280144 reaction equation
[OH:1][CH:2]([C:5]1[CH:10]=[C:9]([N+:11]([O-])=O)[CH:8]=[C:7]([N+:14]([O-])=O)[CH:6]=1)[CH2:3][OH:4]>CO.[Pd]>[OH:1][CH:2]([C:5]1[CH:6]=[C:7]([NH2:14])[CH:8]=[C:9]([NH2:11])[CH:10]=1)[CH2:3][OH:4]

Participants

4

Reactant 1

HCID 18429350HCID 18429350, compound

Product 1

HCID 18429180HCID 18429180, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

1-(1,2-Dihydroxyethyl)-3,5-dinitrobenzene (0.10 g, 0.44 mmol) was dissolved in methanol (35 ml) and hydrogenation was carried out at 60 psi using a Pd/C catalyst 10%, 50 mg). The catalyst was filtered off and the solution was evaporated. Yield: 0.074 g (100%).

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe solution was evaporated

Sources & evidence

ORD record
ord-f4822ccc6d9440138b5a2e1d024697e6
Source dataset
uspto-grants-2002_09
Patent number
US06448442B1

Reaction notes

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