Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1280154Generated: October 26, 2026

1-Acetoxy-2-bromoethane → 5-[N'-(2-Acetoxyethyl)-2-acetoxypropionylamino]-3-acetoxymethyl-N-(2,3-di-acetoxypropyl)-2,4,6-triiodobenzamide

https://huagongshe.com/reaction/1280154

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Acetoxy-2-bromoethaneHCID 13564—
Reactant5-(2-Acetoxypropionylamino)-3-acetoxymethyl-N-(2,3-diacetoxypropyl)-2,4,6-triiodobenzamideHCID 18429188—
Product5-[N'-(2-Acetoxyethyl)-2-acetoxypropionylamino]-3-acetoxymethyl-N-(2,3-di-acetoxypropyl)-2,4,6-triiodobenzamideHCID 1842926395%

Reaction Steps

5-(2-Acetoxypropionylamino)-3-acetoxymethyl-N-(2,3-diacetoxypropyl)-2,4,6-triiodobenzamide was alkylated with 2-bromoethyl acetate according to the general procedure described in Example 25a. After work up the product was isolated in 95% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06448442B1
Source datasetuspto-grants-2002_09
ORD IDord-5f69541a14734667b20bac1dc5c93665
Source noteuspto-grants-2002_09