Thionyl Chloride → HCID 54489353, compound

HRID 1280312Notes

Reaction equation

HRID 1280312 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]=[CH:11][C:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:13])=[CH:6][CH:5]=1)(O)=[O:2].S(Cl)([Cl:22])=O>>[Cl:22][C:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]=[CH:11][C:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:13])=[CH:6][CH:5]=1)=[O:2]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 39957814-Carboxychalcone

Product 1

HCID 54489353HCID 54489353, compoundYield 101%

Procedure

A 1-L reaction vessel was charged with 80.0 g (0.32 mole) of 4-carboxychalcone and 377.7 g (3.17 mole) of thionyl chloride, and heated under reflux for 1 hour. Thereafter, thionyl chloride was removed by distilling, and thus 87.0 g of 4-(chlorocarbonyl)-chalcone was obtained (101% yield). This reaction is shown by the reaction formula in FIG. 1(b).

Workup

  1. temperatureheated
  2. temperatureunder reflux for 1 hour
  3. customThereafter, thionyl chloride was removed
  4. distillationby distilling

Sources & evidence

ORD record
ord-26a10d6c4de1424d9da836031ce9ba82
Source dataset
uspto-grants-2002_09
Patent number
US06451392B1

Reaction notes

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