HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl glycidyl ether → N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3 (phenylmethoxy)propyl]piperazinyl}acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl glycidyl ether | HCID 94247 | — |
| Reactant | N-(2,6-dimethylphenyl)-2-[4-(2-hydroxy-3-indan-2-yloxypropyl)piperazinyl]acetamide | HCID 10181578 | — |
| Reactant | 2-(Oxiran-2-ylmethoxy)indane | HCID 15580339 | — |
| Product | N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3 (phenylmethoxy)propyl]piperazinyl}acetamide | HCID 10273063 | — |
Reaction Steps
Compound 11 was prepared in a similar manner to compound 7, substituting the commercially available benzyl glycidyl ether for 2-(oxiran-2-ylmethoxy)indane in part D to afford 11. Mass Spectrum (M+1)=412.36.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06451798B2 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-ebabdad0806e42f69748ceb0c05e0839 |
| Source note | uspto-grants-2002_09 |