HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dimethoxybenzyl alcohol → 2-(4-{3-[(2,4-dimethoxyphenyl)methoxy]-2-hydroxypropyl}piperazinyl)N-(2,6-dimethylphenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dimethoxybenzyl alcohol | HCID 81750 | — |
| Reactant | N-(2,6-dimethylphenyl)-2-[4-(2-hydroxy-3-indan-2-yloxypropyl)piperazinyl]acetamide | HCID 10181578 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 2-(4-{3-[(2,4-dimethoxyphenyl)methoxy]-2-hydroxypropyl}piperazinyl)N-(2,6-dimethylphenyl)acetamide | HCID 10298973 | — |
Reaction Steps
Compound 19 was prepared in a similar manner to compound 7, substituting the commercially available 2,4-dimethoxy-benzylalcohol for 2-propanol in part C. MS (M+1)=472.42
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06451798B2 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-f72b59258891492b8400991a9aad1b3e |
| Source note | uspto-grants-2002_09 |