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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1280427Generated: October 31, 2026

2-Naphthalenemethanol → N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-naphthylmethoxy)propyl]piperazinyl}acetamide

https://huagongshe.com/reaction/1280427

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-NaphthalenemethanolHCID 74128—
ReactantN-(2,6-dimethylphenyl)-2-[4-(2-hydroxy-3-indan-2-yloxypropyl)piperazinyl]acetamideHCID 10181578—
SolventIsopropanolHCID 3776—
ProductN-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-naphthylmethoxy)propyl]piperazinyl}acetamideHCID 10204920—

Reaction Steps

Compound 25 was prepared in a similar manner to compound 7, substituting the commercially available 2-naphthylmethanol for 2-propanol in part C. MS (M+1)=462.41

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06451798B2
Source datasetuspto-grants-2002_09
ORD IDord-f466de8830a945cd9400edb186be570a
Source noteuspto-grants-2002_09