Thionyl Chloride → HCID 12018227, compound

HRID 1280441Notes

Reaction equation

HRID 1280441 reaction equation
[F:1][C:2]1[CH:22]=[CH:21][CH:20]=[CH:19][C:3]=1[CH2:4][N:5]1[C:9]2=[N:10][CH:11]=[CH:12][CH:13]=[C:8]2[C:7]([C:14]2[O:15][CH:16]=[CH:17][CH:18]=2)=[N:6]1.[S:23](Cl)([Cl:25])=[O:24]>>[F:1][C:2]1[CH:22]=[CH:21][CH:20]=[CH:19][C:3]=1[CH2:4][N:5]1[C:9]2=[N:10][CH:11]=[CH:12][CH:13]=[C:8]2[C:7]([C:14]2[O:15][C:16]([S:23]([Cl:25])=[O:24])=[CH:17][CH:18]=2)=[N:6]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 12018224HCID 12018224, compound

Product 1

HCID 12018227HCID 12018227, compound

Procedure

0.85 g (2.86 mmol) of 1-(2-fluorobenzyl)-3-(2-furyl)pyrazolo[3,4-b]pyridine is stirred with 20 ml of thionyl chloride for 25 min at 70° C. The batch is then evaporated in vacuo and reacted further in crude form.

Workup

  1. customThe batch is then evaporated in vacuo
  2. customreacted further in crude form

Sources & evidence

ORD record
ord-1eda82ed0a924616967d4d0c0976fe12
Source dataset
uspto-grants-2002_09
Patent number
US06451805B1

Reaction notes

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