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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 12805Generated: October 30, 2026

Hydrochloric Acid → HCID 86615966, compound

https://huagongshe.com/reaction/12805

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 24758089HCID 24758089—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 86615966HCID 86615966—

Reaction Steps

5-(2-fluoro-5-methyl-3-pyridinyl)-1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-2,4(1H,3H)-pyrimidinedione was dissolved in dioxane (1 ml) and treated with 4N HCl in dioxane solution (2 eq), to give 59 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07727988B2
Source datasetuspto-grants-2010_06
ORD IDord-bd53ddc60b2944e49de2e72a6026d306
Source noteuspto-grants-2010_06