HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylorthoaceate → N1-[3-(2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylorthoaceate | HCID 21875354 | — |
| Reactant | N1-{3-[(3-nitroquinolin-4-yl)amino]propyl}benzamide | HCID 23512704 | — |
| Product | N1-[3-(2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl]benzamide | HCID 23512664 | — |
Reaction Steps
Using the general method of Example 11 Part C, N1-{3-[(3-nitroquinolin-4-yl)amino]propyl}benzamide (2.0 g, 5.7 mmol) was reduced to the diamine and then reacted with triethylorthoacetate to provide 0.74 g of N1-[3-(2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl]benzamide as a sticky dark yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06451810B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-88e5acb6f119495480e03ebfe0eaf523 |
| Source note | uspto-grants-2002_09 |