HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15336967, compound → 1,4-Dioxaspiro[4.5]decan-8-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15336967 | HCID 15336967 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1,4-Dioxaspiro[4.5]decan-8-amine | HCID 14634315 | 91.4% |
Reaction Steps
To a solution of 1,4-dioxaspiro[4.5]decan-8-one oxime (68 g, 400 mmol) in ethanol (200 mL) was added Raney Nickel as a suspension in ethanol (52 mL). The resulting mixture was shaken at 50 psi of hydrogen for 18 hours. The reaction was filtered and concentrated in vacuo to give 57.5g of 1,4-dioxaspiro[4.5]dec-8-ylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06451804B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-a718896bbf25423291f203569aedbe5f |
| Source note | uspto-grants-2002_09 |