Chloromethyl Methyl Ether → HCID 20284407, compound

HRID 128060Notes

Reaction equation

HRID 128060 reaction equation
[CH3:1][O:2][CH2:3][C:4]1[CH:14]=[CH:13][CH:12]=[CH:11][C:5]=1[NH:6][C:7](=[O:10])[CH2:8][Cl:9].[CH3:15][O:16][CH2:17]Cl>>[CH3:1][O:2][CH2:3][C:4]1[CH:14]=[CH:13][CH:12]=[CH:11][C:5]=1[N:6]([CH2:15][O:16][CH3:17])[C:7](=[O:10])[CH2:8][Cl:9]

Participants

3

Reactant 2

HCID 7864Chloromethyl Methyl EtherHCID 12818264HCID 12818264, compound

Product 1

HCID 20284407HCID 20284407, compound

Procedure

Following the above procedure, but using 2'-(methoxymethyl)-2-chloroacetanilide as the sec-amide starting material and chloromethyl methyl ether as the alkylating agent, the product 2'-(methoxymethyl)-N-(methoxymethyl)-2-chloroacetanilide was obtained.

Sources & evidence

ORD record
ord-4fc4063eb1214e279aff3da87180987b
Source dataset
uspto-grants-1981_03
Patent number
US04258196

Reaction notes

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