Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | N-(tert-butyl)-N'-[2-hydroxy-1-(3-nitrophenyl)ethyl]thiourea | HCID 22747831 | — |
| Produkt | HCID 22747938 | HCID 22747938 | — |
Reaktionsschritte
The process is performed as in Example 2, starting with 4.77 g of N-(tert-butyl)-N′-[2-hydroxy-1-(3-nitrophenyl)ethyl]thiourea and 44 cm3 of aqueous 6N hydrochloric acid, and this mixture is maintained at a temperature in the region of 100° C. for 2 h 30 min. After an identical work-up, 3.1 g of 4-(3-nitrophenyl)-4,5-dihydro-1,3-thiazol-2-ylamine hydrochloride are obtained in the form of a cream-colored solid melting at 232° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US06451821B1 |
|---|
| Quelldatensatz | uspto-grants-2002_09 |
|---|
| ORD ID | ord-88d7da324ea7422c9eff8a325bde6e12 |
|---|
| Quellennotiz | uspto-grants-2002_09 |
|---|
