4-Phenylbutanal → HCID 9858601, compound

HRID 1280695Notes

Reaction equation

HRID 1280695 reaction equation
Br.[NH:2]1[CH2:6][CH2:5][C@H:4]([S:7][C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)[CH2:3]1.[C:15]1([CH2:21][CH2:22][CH2:23][CH:24]=O)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>C(Cl)(Cl)Cl>[C:15]1([CH2:21][CH2:22][CH2:23][CH2:24][N:2]2[CH2:6][CH2:5][C@H:4]([S:7][C:8]3[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=3)[CH2:3]2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 290304-PhenylbutanalHCID 69926498HCID 69926498, compound

Product 1

HCID 9858601HCID 9858601, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound, MS: m/e=328.3 (M+H+) and [α]D20=−6.26° (c=0.61, chloroform) was prepared from (S)-4-(pyrrolidin-3-yl-sulfanyl)-phenol hydrobromide and 4-phenyl-butyraldehyde.

Sources & evidence

ORD record
ord-99e312f1f24f49b495b723bcdce5d17e
Source dataset
uspto-grants-2002_09
Patent number
US06451819B2

Reaction notes

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