3-Benzylcyclobutan-1-one → HCID 178527368, compound

HRID 1280697Notes

Reaction equation

HRID 1280697 reaction equation
FC(F)(F)C(O)=O.[NH:8]1[CH2:12][CH2:11][CH:10]([S:13]([C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=2)(=[O:15])=[O:14])[CH2:9]1.[CH2:23]([CH:30]1[CH2:33][C:32](=O)[CH2:31]1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:23]([C@H:30]1[CH2:31][C@H:32]([N:8]2[CH2:12][CH2:11][CH:10]([S:13]([C:16]3[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=3)(=[O:15])=[O:14])[CH2:9]2)[CH2:33]1)[C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 5760853-Benzylcyclobutan-1-oneHCID 18425771(RS)-4-(Pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acid

Product 1

HCID 178527368HCID 178527368, compound

Procedure

The title compound, MS: m/e=372.3 (M+H+) was prepared from (RS)-4-(pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acid salt and 3-benzyl-cyclobutanone.

Sources & evidence

ORD record
ord-677960731f2a4fb1baf91b14aab851c0
Source dataset
uspto-grants-2002_09
Patent number
US06451819B2

Reaction notes

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