4-Phenylbutanal → HCID 18425776, compound

HRID 1280705Notes

Reaction equation

FC(F)(F)C(O)=O.[NH:8]1[CH2:12][CH2:11][CH:10]([S:13]([C:16]2[CH:17]=[C:18]3[C:22](=[CH:23][CH:24]=2)[NH:21][C:20](=[O:25])[CH2:19]3)(=[O:15])=[O:14])[CH2:9]1.[C:26]1([CH2:32][CH2:33][CH2:34][CH:35]=O)[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[C:26]1([CH2:32][CH2:33][CH2:34][CH2:35][N:8]2[CH2:12][CH2:11][CH:10]([S:13]([C:16]3[CH:17]=[C:18]4[C:22](=[CH:23][CH:24]=3)[NH:21][C:20](=[O:25])[CH2:19]4)(=[O:15])=[O:14])[CH2:9]2)[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

Participants

Reactant 2

HCID 290304-Phenylbutanal

HCID 69923571HCID 69923571, compound

Product 1

HCID 18425776HCID 18425776, compound

Procedure

The title compound, MS: m/e=399.4 (M+H+) was prepared from (RS)-5-(pyrrolidine-3-sulfonyl)-1,3-dihydro-indol-2-one trifluoroacetic acid and 4-phenyl-butyraldehyde.

Sources & evidence

ORD record: ord-6337e56210e94efdb1442c286b6812e7
Source dataset: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06451819B2

Reaction notes

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