4-Phenylbutanal → HCID 18425829, compound
Reaction equation
Br.[NH:2]1[CH2:7][CH2:6][CH2:5][CH:4]([S:8][C:9]2[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=2)[CH2:3]1.[C:16]1([CH2:22][CH2:23][CH2:24][CH:25]=O)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:16]1([CH2:22][CH2:23][CH2:24][CH2:25][N:2]2[CH2:7][CH2:6][CH2:5][CH:4]([S:8][C:9]3[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=3)[CH2:3]2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1Participants
3
Procedure
The title compound, MS: m/e=342.3 (M+H+) was prepared from (RS)-4-(piperidin-3-yl-sulfanyl)-phenol hydrobromide and 4-phenyl-butyraldehyde.
Sources & evidence
- ORD record
- ord-cc48e93ae87e4fc484070ad381aaa845
- Source dataset
- uspto-grants-2002_09
- Patent number
- US06451819B2
Reaction notes
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