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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1280709Generated: October 25, 2026

(5-Bromopentyl)benzene → (RS)-4-[1-(5-Phenyl-pentyl)-pyrrolidine-3-sulfonyl]-phenol

https://huagongshe.com/reaction/1280709

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(5-Bromopentyl)benzeneHCID 285561—
Reactant(RS)-4-(Pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acidHCID 18425771—
Product(RS)-4-[1-(5-Phenyl-pentyl)-pyrrolidine-3-sulfonyl]-phenolHCID 18425828—

Reaction Steps

The title compound, MS: m/e=374.4 (M+H+) was prepared from (RS)-4-(pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acid salt and (5-bromo-pentyl)-benzene. (5-Bromo-pentyl)-benzene is a known compound and has been prepared as described in the following reference: J. Thomas; W. Marlow; J. Med. Chem.; 6; 1963; 107-111.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06451819B2
Source datasetuspto-grants-2002_09
ORD IDord-5913ce2139c8479697a50f3b5071fbf4
Source noteuspto-grants-2002_09