HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-4-(pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acid → (2S,3S)-4-[1-(2-Fluoro-4-phenyl-butyl)-pyrrolidine-3-sulfonyl]-phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-4-(pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acid | HCID 69924492 | — |
| Reactant | (RS)-toluene-4-sulfonic acid 2-fluoro-4-phenyl-butyl ester | HCID 86584022 | — |
| Product | (2S,3S)-4-[1-(2-Fluoro-4-phenyl-butyl)-pyrrolidine-3-sulfonyl]-phenol | HCID 10134204 | — |
Reaction Steps
The title compound, MS: m/e=378.3 (M+H+) was prepared from (S)-4-(pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acid salt and (RS)-toluene-4-sulfonic acid 2-fluoro-4-phenyl-butyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06451819B2 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-2a6f2d7328dc430e9d40c457d982dc09 |
| Source note | uspto-grants-2002_09 |