2-(2-Phenylethyl)oxirane → HCID 9924192, compound

HRID 1280715Notes

Reaction equation

HRID 1280715 reaction equation
FC(F)(F)C(O)=O.[NH:8]1[CH2:12][CH2:11][C@@H:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][CH:15]=2)[CH2:9]1.[CH2:21]([CH:29]1[CH2:31][O:30]1)[CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[OH:30][C@@H:29]([CH2:21][CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[CH2:31][N:8]1[CH2:12][CH2:11][C@@H:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][CH:15]=2)[CH2:9]1

Participants

3

Reactant 2

HCID 1359552-(2-Phenylethyl)oxiraneHCID 69924259HCID 69924259, compound

Product 1

HCID 9924192HCID 9924192, compound

Procedure

The title compound, MS: m/e=344.4 (M+H+) was prepared from (R)-4-(pyrrolidin-3-yl-sulfanyl)-phenol trifluoro-acetic acid and (RS)-2-phenethyl-oxirane.

Sources & evidence

ORD record
ord-3507e86f4c3f4d0090f4ad46f2f1f9d8
Source dataset
uspto-grants-2002_09
Patent number
US06451819B2

Reaction notes

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