2-(2-Phenylethyl)oxirane → HCID 18425804, compound

HRID 1280717Notes

Reaction equation

HRID 1280717 reaction equation
Br.[NH:2]1[CH2:7][CH2:6][CH2:5][CH:4]([S:8][C:9]2[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=2)[CH2:3]1.[CH2:16]([CH:24]1[CH2:26][O:25]1)[CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[OH:25][CH:24]([CH2:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH2:26][N:2]1[CH2:7][CH2:6][CH2:5][CH:4]([S:8][C:9]2[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=2)[CH2:3]1

Participants

3

Reactant 2

HCID 1359552-(2-Phenylethyl)oxiraneHCID 18425848HCID 18425848, compound

Product 1

HCID 18425804HCID 18425804, compound

Procedure

The title compound, MS: m/e=358.2 (M+H+) was prepared from (RS)-4-(piperidin-3-yl-sulfanyl)-phenol hydrobromide and (RS)-2-phenethyl-oxirane.

Sources & evidence

ORD record
ord-161795523cbf4d26a867c40b38d3db2e
Source dataset
uspto-grants-2002_09
Patent number
US06451819B2

Reaction notes

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