HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Iodo-2-(methoxymethoxy)benzene → (RS)-4-{1-[4-(2-Methoxymethoxy-phenyl)-butyl]-pyrrolidine-3-sulfonyl}-phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Iodo-2-(methoxymethoxy)benzene | HCID 11747465 | — |
| Reactant | (RS)-4-(1-but-3-enyl-pyrrolidine-3-sulfonyl)-phenol | HCID 18425811 | — |
| Product | (RS)-4-{1-[4-(2-Methoxymethoxy-phenyl)-butyl]-pyrrolidine-3-sulfonyl}-phenol | HCID 18425864 | — |
Reaction Steps
The title compound, MS: m/e=420.3 (M+H+) was prepared from (RS)-4-(1-but-3-enyl-pyrrolidine-3-sulfonyl)-phenol and 1-iodo-2-methoxymethoxy-benzene. 1-Iodo-2-methoxymethoxy-benzene is a known compound and has been prepared as described in the following reference: J. R. Labrosse; C. Poncet; P. Lhoste; D. Sinou; Tetrahedron, Asymmetry; 10; 6; 1999; 1069-1078.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06451819B2 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-53c8fe976c0b43609f2ec65536de246e |
| Source note | uspto-grants-2002_09 |