5-Chloro-3-(trifluoromethyl)benzene-1,2-diamine → HCID 178518438, compound

HRID 1281114Notes

Reaction equation

HRID 1281114 reaction equation
[CH:1]([C:3]1[CH:16]=[CH:15][C:6]([CH:7]=[C:8]2[S:12][C:11](=[O:13])[NH:10][C:9]2=[O:14])=[CH:5][CH:4]=1)=O.[Cl:17][C:18]1[CH:19]=[C:20]([C:26]([F:29])([F:28])[F:27])[C:21]([NH2:25])=[C:22]([NH2:24])[CH:23]=1>>[Cl:17][C:18]1[CH:19]=[C:20]([C:26]([F:27])([F:28])[F:29])[C:21]2[NH:25][C:1]([C:3]3[CH:16]=[CH:15][C:6]([CH:7]=[C:8]4[S:12][C:11](=[O:13])[NH:10][C:9]4=[O:14])=[CH:5][CH:4]=3)=[N:24][C:22]=2[CH:23]=1

Participants

3

Reactant 2

HCID 27734985-Chloro-3-(trifluoromethyl)benzene-1,2-diamineHCID 32727725-(4-Formylbenzylidene)-2,4-thiazolidinedione

Product 1

HCID 178518438HCID 178518438, compound

Procedure

6-Chloro-2-[4-[(2,4-dioxothiazolidin-5-ylidene)methyl]phenyl]-4-(trifluoromethyl)benzimidazole was prepared from 5-(4-formylbenzylidene)-2,4-thiazolidinedione and 5-chloro-3-trifluoromethyl-1,2-phenylenediamine by following General Procedure 2.

Sources & evidence

ORD record
ord-09c0f61479d9406487290390e2fbb58b
Source dataset
uspto-grants-2002_09
Patent number
US06452014B1

Reaction notes

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