4-Trifluoromethyl-1,2-phenylenediamine → HCID 178518435, compound

HRID 1281115Notes

Reaction equation

HRID 1281115 reaction equation
[CH:1]([C:3]1[CH:16]=[CH:15][C:6]([CH:7]=[C:8]2[S:12][C:11](=[O:13])[NH:10][C:9]2=[O:14])=[CH:5][CH:4]=1)=O.[F:17][C:18]([F:28])([F:27])[C:19]1[CH:24]=[CH:23][C:22]([NH2:25])=[C:21]([NH2:26])[CH:20]=1>>[O:13]=[C:11]1[NH:10][C:9](=[O:14])[C:8](=[CH:7][C:6]2[CH:15]=[CH:16][C:3]([C:1]3[NH:26][C:21]4[CH:20]=[C:19]([C:18]([F:17])([F:27])[F:28])[CH:24]=[CH:23][C:22]=4[N:25]=3)=[CH:4][CH:5]=2)[S:12]1

Participants

3

Reactant 2

HCID 5208224-Trifluoromethyl-1,2-phenylenediamineHCID 32727725-(4-Formylbenzylidene)-2,4-thiazolidinedione

Product 1

HCID 178518435HCID 178518435, compound

Procedure

2-[4-[(2,4-Dioxothiazolidin-5-ylidene)methyl]phenyl]-5-trifluoromethylbenzimidazole was prepared from 5-(4-formylbenzylidene)-2,4-thiazolidinedione and 4-trifluoromethyl-1,2-phenylenediamine by following General Procedure 2.

Sources & evidence

ORD record
ord-8e6363f302984029b51360a99b1beaaa
Source dataset
uspto-grants-2002_09
Patent number
US06452014B1

Reaction notes

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