N,N-Dimethylaminoethyl chloride hydrochloride → HCID 18426781, compound

HRID 1281127Notes

Reaction equation

HRID 1281127 reaction equation
[Cl:1][C:2]1[C:18]([Cl:19])=[CH:17][C:5]2[N:6]=[C:7]([C:9]3[CH:14]=[CH:13][C:12]([CH:15]=[O:16])=[CH:11][CH:10]=3)[NH:8][C:4]=2[CH:3]=1.Cl.[CH3:21][N:22]([CH3:26])[CH2:23][CH2:24]Cl>>[Cl:19][C:18]1[C:2]([Cl:1])=[CH:3][C:4]2[N:8]([CH2:24][CH2:23][N:22]([CH3:26])[CH3:21])[C:7]([C:9]3[CH:10]=[CH:11][C:12]([CH:15]=[O:16])=[CH:13][CH:14]=3)=[N:6][C:5]=2[CH:17]=1

Participants

3

Reactant 2

HCID 11636816N,N-Dimethylaminoethyl chloride hydrochlorideHCID 184267935,6-Dichloro-2-(4-formylphenyl)benzimidazole

Product 1

HCID 18426781HCID 18426781, compound

Procedure

5,6-Dichloro-1-(2-dimethylaminoethyl)-2-(4-formylphenyl)benzimidazole was prepared from 5,6-dichloro-2-(4-formylphenyl)benzimidazole obtained in Example 13 and 2-(dimethylamino)ethyl chloride hydrochloride by following General Procedure 3.

Sources & evidence

ORD record
ord-37fc4391e84243e99615dfcb6f7f8313
Source dataset
uspto-grants-2002_09
Patent number
US06452014B1

Reaction notes

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