Methyl 4-(bromomethyl)benzoate → HCID 18426827, compound

HRID 1281128Notes

Reaction equation

HRID 1281128 reaction equation
[Cl:1][C:2]1[C:18]([Cl:19])=[CH:17][C:5]2[N:6]=[C:7]([C:9]3[CH:14]=[CH:13][C:12]([CH:15]=[O:16])=[CH:11][CH:10]=3)[NH:8][C:4]=2[CH:3]=1.Br[CH2:21][C:22]1[CH:31]=[CH:30][C:25]([C:26]([O:28][CH3:29])=[O:27])=[CH:24][CH:23]=1>>[Cl:19][C:18]1[C:2]([Cl:1])=[CH:3][C:4]2[N:8]([CH2:21][C:22]3[CH:31]=[CH:30][C:25]([C:26]([O:28][CH3:29])=[O:27])=[CH:24][CH:23]=3)[C:7]([C:9]3[CH:10]=[CH:11][C:12]([CH:15]=[O:16])=[CH:13][CH:14]=3)=[N:6][C:5]=2[CH:17]=1

Participants

3

Reactant 2

HCID 256687Methyl 4-(bromomethyl)benzoateHCID 184267935,6-Dichloro-2-(4-formylphenyl)benzimidazole

Product 1

HCID 18426827HCID 18426827, compound

Procedure

Methyl 4-[5,6-dichloro2-(4-formylphenyl)benzimidazol-1-ylmethyl]benzoate was prepared from 5,6-dichloro-2-(4-formylphenyl)benzimidazole obtained in Example 13 and methyl 4-bromomethylbenzoate by following General Procedure 3.

Sources & evidence

ORD record
ord-c1f17e2c2264425d99cc5d8eb292faea
Source dataset
uspto-grants-2002_09
Patent number
US06452014B1

Reaction notes

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