Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 67940172 | HCID 67940172 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 9868506 | HCID 9868506 | 90% |
Reaction Steps
The compound (3-a)(0.305 g) was dissolved in the solvent mixture (acetic acid:THF:water=2:1:1)(6 ml) and the solution was maintained at 50° C. for 14 hours. The crude product obtained by the conventional treatment was purified on silica gel column to give the titled compound (4-a)[yield:0.213 g(90%)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06452039B1 |
|---|
| Source dataset | uspto-grants-2002_09 |
|---|
| ORD ID | ord-befb248d702145b4a1ed684ce0b5fc86 |
|---|
| Source note | uspto-grants-2002_09 |
|---|
