HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18426939, compound → hexahydro-2H-cyclopenta[b]furan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18426939 | HCID 18426939 | — |
| Reactant | HCID 131722602 | HCID 131722602 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | hexahydro-2H-cyclopenta[b]furan-2-one | HCID 11665410 | 58% |
Reaction Steps
The compound (9-a) was reacted with dimethyl-3,3-difluoro-2-oxoheptylphosphonate (30.0 g) in dichloromethane in the presence of thallium methoxide (8.23 ml). The crude product obtained by the conventional treatment of the reaction mixture was purified on silica gel column to give the titled compound (10-a) [yield:24.4 g(58%)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06452039B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-d5015ca34c964aec9c9fddb4be78e4f0 |
| Source note | uspto-grants-2002_09 |