1-Bromo-3,5-di-tert-butylbenzene → (Z)-4-[2-(3,5-Di-tert-butylphenyl)-2-trimethylsilanylvinyl]benzyl Alcohol

Participants

Reaction Steps

Following General Procedure A, 4-[(trimethylsilyl)ethynyl]benzyl tert-butyldiphenylsilyl ether and 1-bromo-3,5-Di-tert-butylbenzene (which can be prepared by the procedure described in Komen and Bickel Synth. Commun, 1996, 26, 1693-1698) were coupled to give the title compound (Compound 32). PNMR (300 MHz, CDCl3) δ7.40 (s, 4H), 7.33 (s, 2H), 7.08 (s, 1H), 7.07(s, 1H), 4.78 (d, J=5.9 Hz, 1H), 1.41 (s, 18H), 0.00 (s, 9H).

Provenance & Evidence