HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → (S)-N-(4-(Oxiran-2-ylmethoxy)phenyl)methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | N-(4-phenylmethoxyphenyl)methanesulfonamide | HCID 669037 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | (S)-N-(4-(Oxiran-2-ylmethoxy)phenyl)methanesulfonamide | HCID 11322479 | — |
Reaction Steps
N-[4-(Benzyloxy)phenyl]methanesulfonamide (3.0 g, 10.8 mmol) was dissolved in ethanol (150 mL). 10% Palladium on carbon (0.3 g) was added and the mixture shaken overnight under 50 psi hydrogen on a Parr apparatus. The solution was filtered through a Celite pad and the solvent removed to yield the title compound (1.32 g, 7.4 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06451814B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-eabd99f35814487eaeb1cd226ed336db |
| Source note | uspto-grants-2002_09 |