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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1281509Generated: November 3, 2026

Tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenylsilane → HCID 10302914, compound

https://huagongshe.com/reaction/1281509

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenylsilaneHCID 12045564—
ReactantHCID 18173519HCID 18173519—
SolventChloroform methanolHCID 21584188—
ProductHCID 10302914HCID 1030291429.4%

Reaction Steps

4-[4-(2-Aminoethyl)anilino]-N-(3,5-difluorobenzyl)-1-piperidinecarboxamide formamide (0.33 g, 0.76 mmol) was reacted with tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenyl-silane (0.276 g, 0.68 mmol) according to Procedure G (eluant: 20:1 chloroform-methanol) to give the title compound (0.165 g, 0.20 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06451814B1
Source datasetuspto-grants-2002_09
ORD IDord-b093e13b831e47cdaf0ccb25c6658a7d
Source noteuspto-grants-2002_09