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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1281513Generated: October 28, 2026

Tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenylsilane → HCID 10119515, compound

https://huagongshe.com/reaction/1281513

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenylsilaneHCID 12045564—
ReactantHCID 18173890HCID 18173890—
SolventChloroform methanolHCID 21584188—
ProductHCID 10119515HCID 1011951525%

Reaction Steps

4-[4-(2-Aminoethyl)anilino]-N-(2-fluorobenzyl)-1-piperidinecarboxamide (0.50 g, 1.2 mmol) was reacted with tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenyl-silane (0.436 g, 1.08 mmol) according to Procedure G (eluant: 20:1 chloroform-methanol) to give the title compound (0.21 g, 0.27 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06451814B1
Source datasetuspto-grants-2002_09
ORD IDord-6ab926f7c09243f898d6bc3259759bc4
Source noteuspto-grants-2002_09