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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1281523Generated: November 2, 2026

Tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenylsilane → HCID 10302915, compound

https://huagongshe.com/reaction/1281523

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenylsilaneHCID 12045564—
ReactantHCID 69987384HCID 69987384—
SolventChloroform methanolHCID 21584188—
ProductHCID 10302915HCID 1030291520.9%

Reaction Steps

4-[4-(2-Aminoethyl)anilino]-N-(2,6-difluorobenzyl)-1-piperidinecarboxamide formate (0.50 g, 1.15 mmol) was reacted with tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenyl-silane (0.465 g, 1.15 mmol) according to Procedure G (eluant: 20:1 chloroform-methanol) to give the title compound (0.192 g, 0.24 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06451814B1
Source datasetuspto-grants-2002_09
ORD IDord-9abede72a9bb4667a0e1929b3c2655ea
Source noteuspto-grants-2002_09