反应详情

温度

87.5 °C

A mixture of the above pyrazolone, (VIk) (10 mg, 0.047 mmol), 5,6-methylenedioxy-1-methyl-indole-3-carboxaldehyde (11 mg, 0.054 mmol) in 1 mL of absolute ethanol along with a drop of piperidine was kept under stirring at 85-90° C. A solid separated. After 2 h the mixture was cooled to room temperature and the solid was filtered, washed with ethanol and dried to isolate the product (11 mg, 59% yield). MS: 398 (M+H).

1. customA solid separated
2. temperatureAfter 2 h the mixture was cooled to room temperature
3. filtrationthe solid was filtered
4. washwashed with ethanol
5. customdried