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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1281761Generated: October 27, 2026

1-Fluoro-4-methoxy-2-nitrobenzene → Ethyl 2-(4-methoxy-2-nitroanilino)benzo[b]thiophene-3-carboxylate

https://huagongshe.com/reaction/1281761

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Fluoro-4-methoxy-2-nitrobenzeneHCID 565653—
ReactantEthyl 2-amino-1-benzothiophene-3-carboxylateHCID 699464—
SolventDimethyl SulfoxideHCID 679—
ProductEthyl 2-(4-methoxy-2-nitroanilino)benzo[b]thiophene-3-carboxylateHCID 18422251—

Reaction Steps

In the same manner as in Starting Material Synthesis Example 4 and using ethyl 2-aminobenzo[b]thiophene-3-carboxylate, 2-fluoro-5-methoxynitrobenzene and dimethyl sulfoxide, ethyl 2-(4-methoxy-2-nitroanilino)benzo[b]thiophene-3-carboxylate is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06455521B1
Source datasetuspto-grants-2002_09
ORD IDord-923f269dff4940619f4e3382951683c1
Source noteuspto-grants-2002_09