HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Difluoronitrobenzene → 2-(4-Fluoro-2-nitroanilino)benzo[b]thiophene-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Difluoronitrobenzene | HCID 67767 | — |
| Reactant | 2-Amino-1-benzothiophene-3-carbonitrile | HCID 23273581 | — |
| Product | 2-(4-Fluoro-2-nitroanilino)benzo[b]thiophene-3-carbonitrile | HCID 18422298 | 93.1% |
Reaction Steps
In the same manner as in Starting Material Synthesis Example 51 and using 2-aminobenzo[b]thiophene-3-carbonitrile (4.0 g) and 2,5-difluoronitrobenzene (3.7 g), 2-(4-fluoro-2-nitroanilino)benzo[b]thiophene-3-carbonitrile (6.7 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06455521B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-271f4fca96354e5893897184d84c6626 |
| Source note | uspto-grants-2002_09 |