反应详情

Sodium borohydride (0.462 g) was added in one portion to a stirred solution of 7-methoxybenzofuran-2-carbaldehyde (2.15 g) in methanol (50 ml) at room temperature and the reaction was stirred for 3 hours. The reaction mixture was then diluted with water (100 ml) and extracted with dichloromethane (3×30 ml). The organic extracts were combined, washed with water (30 ml), dried over magnesium sulphate, filtered and the solvent removed in vacuo to afford the title compound (2.10 g) as a pale orange liquid.

1. extractionextracted with dichloromethane (3×30 ml)
2. washwashed with water (30 ml)
3. dry with materialdried over magnesium sulphate
4. filtrationfiltered
5. customthe solvent removed in vacuo