HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Fluorophenyl)piperazine → N-(1-methyl-1-(4-((4-(4-fluorophenyl)-piperazin-1-yl)methyl)phenyl)ethyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Fluorophenyl)piperazine | HCID 75260 | — |
| Reactant | N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide | HCID 18423089 | — |
| Product | N-(1-methyl-1-(4-((4-(4-fluorophenyl)-piperazin-1-yl)methyl)phenyl)ethyl)acetamide | HCID 11545168 | — |
Reaction Steps
By similar reaction and treatment to that in Example 1(5) using 1-(4-fluorophenyl)piperazine instead of phenylpiperazine and N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide instead of N-(4-chloromethylphenylmethyl)acetamide, the title compound was obtained as pale-brown crystals, m.p.=104.5-106° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06455528B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-38c3b09c0cf94fb1ab6f46d033d157bd |
| Source note | uspto-grants-2002_09 |