1-(2,4-Difluorophenyl)piperazine dihydrochloride → N-(1-(4-(1-(4-(2,4-difluorophenyl)-piperazin-1-yl)ethyl)phenyl)-1-methylethyl)acetamide

Participants

Reaction Steps

By similar reaction and treatment to that in Example 1(5) using 1-(2,4-difluorophenyl)piperazine dihydrochloride instead of phenylpiperazine and N-(1-(4-(1-chloroethyl)phenyl)-1-methylethyl)acetamide obtained in Example 60(2) instead of N-(4-chloromethylphenylmethyl) acetamide, the title compound was obtained as a white amorphous solid.

Provenance & Evidence