N-(4-(1-benzyloxycarbonylamino-1-methylethyl)phenylmethyl)acetamide → N-(4-(1-amino-1-methylethyl)phenylmethyl)acetamide

Participants

Reaction Steps

To a solution of N-(4-(1-benzyloxycarbonylamino-1-methylethyl)phenylmethyl)acetamide (9.57 g) in methanol (200 ml) and chloroform (200 ml) was added 10% palladium-carbon (5.0 g) and the mixture was stirred for 5 hr while introducing a hydrogen gas. The reaction mixture was passed through Celite and the solvent was evaporated to give the title compound (5.8 g) as a pale-yellow amorphous solid.

Provenance & Evidence