1-(2-Pyridyl)piperazine → N-(1-methyl-1-(4-((4-(pyridin-2-yl)piperazin-1-yl)methyl)phenyl)ethyl)acetamide

Participants

Role	Name	HCID	Charge
Reactant	1-(2-Pyridyl)piperazine	HCID 94459	—
Reactant	N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide	HCID 18423089	—
Product	N-(1-methyl-1-(4-((4-(pyridin-2-yl)piperazin-1-yl)methyl)phenyl)ethyl)acetamide	HCID 11530455	—

Reaction Steps

By similar reaction and treatment to that in Example 1(5) using N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide obtained in Example 95(4) instead of N-(4-chloromethylphenylmethyl)acetamide and 1-(2-pyridyl)piperazine instead of phenylpiperazine, the title compound was obtained as white crystals, m.p.=129-130° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06455528B1
Source dataset	uspto-grants-2002_09
ORD ID	ord-042af475f9154506b3d9a73db2a49e4b
Source note	uspto-grants-2002_09