反应详情

A solution of 1-acetyl-4-(4,6-diethoxypyrimidin-2-yl)piperazine (1.8 g) and sodium hydroxide (1.0 g) in ethanol (10 ml)—water (10 ml) was refluxed under heating for 11 hr. The reaction mixture was poured into water and extracted with chloroform. The extract was dried over anhydrous sodium sulfate and the solvent was evaporated to give the title compound (1.6 g) as a pale-brown oil.

1. temperatureunder heating for 11 hr
2. extractionextracted with chloroform
3. dry with materialThe extract was dried over anhydrous sodium sulfate
4. customthe solvent was evaporated